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cellule souche
Commentaire :
On définit une cellule souche par deux propriétés essentielles :
- La capacité d'auto-renouvellement, c'est-à-dire la capacité à se multiplier à l'identique pour produire de nouvelles cellules souches. - La capacité à donner naissance à des cellules différenciées comme par exemple les globules rouges, les cellules du foie ou les cellules musculaires. (Le point sur les cellules souche, AFM 2006) Synonyme(s)stem cellsVoir aussi |
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4th International Congress of Myology, 4ème colloque international de Myologie (9-13 mai 2011; Lille (France)) ; Lepper C ; Partridge T ; Chen-Ming F | AFM-TELETHON | 2011Skeletal muscle tissue is prone to damage from acute physical trauma such as sport injuries as well as from daily wear and tear: this is managed by its tremendous capacity to repair itself. Cell transplantation and lineage tracing studies have d[...]Article
Sciorati C ; Miglietta D ; Buono R ; Pisa V ; Cattaneo D ; Azzoni E ; Brunelli S ; Clementi E | 2011Accès au résumé PubMed / to PubMed abstract 28/08/2011 - Le NCX 320, un dérivé de l’ibuprofène, permet de ralentir la progression de la dystrophie musculaire à long-terme chez la souris L’oxide nitrique (NO) est impliqué dans la p[...]Article
AFM-TELETHON 2011Mesoangioblasts are recently characterized progenitor cells, associated with the vasculature and able to differentiate into different types of solid mesoderm, including skeletal muscle (Minasi et al. Development 129, 2773, 2002). When wild type [...]Article
Wang B ; Miyagoe-Suzuki Y ; Yada E ; Ito N ; Nishiyama T ; Nakamura M ; Ono Y ; Motohashi N ; Segawa M ; Masuda S ; Takeda S | 2011Accès au résumé PubMed / to PubMed abstractArticle
Moorwood C ; Lozynska O ; Suri N ; Napper AD ; Diamond SL ; Khurana TS | 2011Accès au résumé PubMed / to PubMed abstract 02/02/2012 - Le nabumetone, une nouvelle molécule qui augmente l’expression de l’utrophine dans des cultures de cellules La dystrophie musculaire de Duchenne (DMD), liée à une mutation dans[...]Article
Cheli S ; François S ; Bodega B ; Ferrari F ; Tenedini E ; Roncaglia E ; Ferrari S ; Ginelli E ; Meneveri R | 2011Accès au résumé PubMed / to PubMed abstractArticle
Vanderplanck C ; Ansseau E ; Charron S ; Stricwant N ; Tassin A ; Laoudj-Chenivesse D ; Wilton SD ; Coppée F ; Belayew A | 2011Accès au résumé PubMed / to PubMed abstractArticle
AFM-TELETHON 2011The lack of existing models of pathologic tissues has rendered many important questions in disease pathogenesis inaccessible. Human embryonic stem cells derived from affected embryos during a pre-implantation diagnostic (PGD), as well as the tec[...]Article
Valadares M ; Zucconi E ; Secco M ; Bueno Junior C ; Brandalise V ; Assoni A ; Gomes J ; Landini V ; Andrade T ; Lima B ; Vainzof M ; Zatz M | AFM-TELETHON | 2011The possibility to use stem-cells in the future as a therapy for progressive muscular dystrophies has been of great interest. However, many questions still need to be addressed. What is the best way of delivery: local or systemic? What are the b[...]Article
AFM-TELETHON 2011During development, founder stem cells proliferate, and cell cycle exit is generally restricted to differentiating cells. In contrast, adult stem cells, can assume different cellular states, either quiescence or proliferating. After embryonic de[...]Thèse/Mémoire
Lescroart F, Auteur | 2011Le développement cardiaque implique deux lignages cellulaires, dont un correspond au second champ cardiaque qui contribue aux pôles veineux et artériel du coeur. De manière intéressante, une partie des muscles squelettiques antérieurs, non-somit[...]Rapport institutionnel
Rapport institutionnel
European Medicines Agency | 2011Le but de cette réflexion est de couvrir tous les aspects relatifs aux produits médicaux issus des cellules souches en vue du "Marketing Authorisation Application".Reco PNDS
The retina contains photoreceptors that convert light signals into electric signals, further transmitted to the brain by different neurons. Any defect involved in these processes of phototransduction and transmission in the retina lead to visual[...]Article
Cacchiareli D ; Cazzella V ; Cesana M ; Incitti T ; Pinnaro C ; Legnini I ; Morlando M ; Bozzoni I | AFM-TELETHON | 2011MicroRNAs are recognized as important regulators of gene expression in the differentiation commitment of several cell types and have been shown to occupy very high hierarchical positions in the cascade of regulatory events controlling cell speci[...]Article
The plasminogen activation (PA) system is a mechanism extensively used by the cell for the generation of proteolytic activity in the extracellular matrix, where it contributes to tissue remodeling in a wide range of physiopathological processes.[...]Article
Tedesco FS ; Hoshiya H ; D'Antona G ; Gerli MFM ; Messina G ; Antonini S ; Tonlorenzi R ; Benedetti S ; Berghella L ; Torrente Y ; Kazuki Y ; Bottinelli R ; Oshimura M | 2011Accès au résumé PubMed / to PubMed abstract 29/09/2011 - La thérapie génique par chromosomes artificiels humains de cellules souches améliore la dystrophie musculaire de Duchenne dans le modèle de souris mdx Les chromosomes artifici[...]Article
Six1 and Six4 are homeoproteins of the Six/sine oculis family. These proteins are expressed continuously during muscle development: in the dermomyotomal hypaxial myogenic progenitors, they control Pax3 expression and myogenic progenitors fate; i[...]Article
Mesirca P ; Torrente A ; Arsic N ; Nargeot J ; Mangoni M ; Lamb N ; Fernandez A | AFM-TELETHON | 2011Adult stem cells can be isolated from skeletal muscle and display spontanous multi-lineage differentiation including towards cardiac lineage. (Arsic et al. 2008)*. Before differentiation and in addition to Sca-1 and Bcrp1/ABCG2, skeletal Muscle-[...]Article
AFM-TELETHON 2011Environment of stem cells plays a crucial role in controlling their fate: quiescence, proliferation, differentiation, self-renewal. Environment of satellite cells comprise endothelial cells, periendothelial cells, immune cells and fibroblastic c[...]Reco PNDS
Our research and development programs are organized into 3 main activities: - Biobanking of human Embryonic Stem (hES) cell lines - Cell culture automation of human Pluripotent Stem (hPS) cells and their progenies - Genomic engineering of hiP[...]Article
Farini A ; Belicchi M ; Parolini D ; Sitzia C ; Cassinelli L ; Del Fraro G ; Razini P ; Angeloni V ; Jardim L ; da Silva Bizario J ; Garcia L ; Torrente I | AFM-TELETHON | 2011In DMD, skeletal and cardiac muscles are affected, leading to wheelchair dependency, respiratory failure and premature death. Recent advances have pointed out a variety of possible therapeutic approaches. A combination of these strategies might [...]Article
Accès au résumé PubMed / to PubMed abstractArticle
AFM-TELETHON 2011Embryonic stem (ES) cells differentiate into multiple lineages during in vitro embryoid body (EB) formation. This makes the ES/EB system a powerful tool to study early embryonic developmental pathways and to generate specific cell populations fo[...]