Title: | Structure-activity relationships of 2-pyrimidinecarbohydrazides as utrophin modulators for the potential treatment of Duchenne muscular dystrophy |
Journal : | Bioorganic & medicinal chemistry, 69 |
Authors: | Chatzopoulou M ; Conole D ; Emer E ; Rowley JA ; Willis NJ ; Squire SE ; Gill B ; Brough S ; Wilson FX ; Wynne GM ; Davies SG ; Davies KE ; Russell AJ |
Material Type: | Article |
Publisher: | England, 05/2022 |
Size: | p 116812 |
Languages: | English |
Keywords : | Duchenne muscular dystrophy ; therapeutical research ; utrophin |
Keywords: | Carbohydrazide;Duchenne muscular dystrophy;LUmdx;Phenotypic screening;Utrophin modulator; |
Pubmed / DOI : | Pubmed : 35772287 / DOI : 10.1016/j.bmc.2022.116812 |
N° Profil MNM : | 2022062 |
Link for e-copy: | http://www.ncbi.nlm.nih.gov/pubmed/35772287 |