Title: | Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction |
Journal : | Brain : a journal of neurology |
Authors: | Van Lent J ; Verstraelen P ; Asselbergh B ; Adriaenssens E ; Mateiu L ; Verbist C ; De Winter V ; Eggermont K ; van den Bosch L ; De Vos WH ; Timmerman V |
Material Type: | Article |
Publisher: | England, 15/06/2021 |
Languages: | English |
Keywords : | axonal forms of CMT ; Charcot-Marie-Tooth disease ; genotype-phenotype correlation ; mouse ; physiopathology ; RESEARCH ; stem cells |
Keywords: | Charcot-Marie-Tooth neuropathy;dual leucine kinase inhibitor;iPSC-derived motor and sensory neurons;mitochondrial dysfunction;phenotyping; |
Pubmed / DOI : | Pubmed : 34128983 / DOI : 10.1093/brain/awab226 |
N° Profil MNM : | 2021061 |
Link for e-copy: | http://www.ncbi.nlm.nih.gov/pubmed/34128983 |