Titre : | Muscle Resonance Imaging pattern recognition in sporadic Inclusion Body Myositis. |
Revue : | Muscle & Nerve, 52, 6 |
Auteurs : | Tasca G ; Monforte M ; De Fino C ; Kley RA ; Ricci E ; Mirabella M |
Type de document : | Article |
Année de publication : | 12/2015 |
Pages : | p. 956-62 |
Langues: | Anglais |
Mots-clés: | IBM ; Inclusion body myositis ; muscle MRI ; pattern recognition ; sensitivity ; specificity |
Résumé : |
INTRODUCTION: In sporadic inclusion body myositis (IBM), additional tools are needed to confirm the diagnosis, particularly in clinically atypical or pathologically unproven patients. The aims of this study were to refine the pattern of muscle MRI in IBM and to assess its accuracy in differentiating IBM frorm other myopathies that overlap with it clinically or pathologically.
METHODS: Blind assessment of the scans of 17 definite IBM, 2 possible IBM, and 118 patients with other myopathies. RESULTS: The diagnostic accuracy to detect definite IBM was 95% for the typical pattern (with 100% specificity) and 97% for both typical and consistent patterns (with 97% specificity). DISCUSSION: Muscle MRI is an accurate tool for diagnostic workup of suspected IBM patients and may be particularly helpful in patients with early disease or who lack the classical IBM pathology. This article is protected by copyright. All rights reserved. |
Pubmed / DOI : | DOI : 10.1002/mus.24661 / Pubmed : 25808807 |
En ligne : | http://www.ncbi.nlm.nih.gov/pubmed/25808807 |