Title: | Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers |
Journal : | Nature medicine, 21, 3 |
Authors: | Goyenvalle A, Author ; Griffith G ; Babbs A ; Andaloussi SE ; Ezzat K ; Avril A ; Dugovic B ; Chaussenot R ; Ferry A ; Voit T ; Amthor H ; Bühr C ; Schürch S ; Wood MJ ; Davies KE ; Vaillend C ; Leumann C ; Garcia L |
Material Type: | Article |
Publication Date: | 2015 |
Size: | p 270 |
Languages: | English |
Keywords : | antisense oligonucleotides ; cell expression ; cross-sectional study ; DNA ; Duchenne muscular dystrophy ; dystrophin ; exon skipping ; heart function ; immunohistochemistry ; mdx mouse ; motor skills ; muscle strength ; nanoparticles ; respiration (macroscopic) ; respiratory plethysmography |
Abstract: |
Comment in:
Muscular dystrophy: New exon-skipping strategy rescues dystrophin. [Nat Rev Drug Discov. 2015] |
Pubmed / DOI : | DOI : 10.1038/nm.3765 / Pubmed : 25642938 |
Link for e-copy: | http://www.ncbi.nlm.nih.gov/pubmed/25642938 |
See also : |