Title: | Safety, tolerability, and pharmacokinetics of PTC124, a nonaminoglycoside nonsense nutation suppressor, following single- and multiple-dose administration to healthy male and female adult volunteers |
Journal : | Journal of clinical pharmacology, 47, 4 |
Authors: | Hirawat S ; Welch EM ; Elfring GL ; Northcutt VJ ; Paushkin S ; Hwang S ; Leonard EM ; Almstead NG ; Ju W ; Peltz SW ; Miller LL |
Material Type: | Article |
Publication Date: | 2007 |
Size: | p. 430-444 |
Languages: | English |
Keywords : | ataluren ; blood ; blood serum ; C-reactive protein ; genetic diseases ; inclusion criteria ; messenger RNA ; molecular biology ; molecular structure ; pharmacokinetics ; phase 1 clinical trials ; serum globulins ; skeletal muscle ; urine |
Abstract: |
Accès au résumé PubMed / to PubMed abstract |
Lien associé : | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17389552&query_hl=1&itool=pubmed_docsum |