Title: | PRO-051, an antisense oligonucleotide for the potential treatment of Duchenne muscular dystrophy |
Journal : | Current opinion in molecular therapeutics, 12, 4 |
Authors: | Hammond SM ; Wood MJA |
Material Type: | Article |
Publication Date: | 2010 |
Size: | p. 478-486 |
Languages: | English |
Keywords : | adverse side effects ; antisense oligonucleotides ; drug toxicity ; Duchenne muscular dystrophy ; DYS gene ; dystrophin ; exon skipping ; genetic mutations ; in vitro ; in vivo ; metabolism ; muscle biopsies ; pharmacokinetics ; pharmacotherapy ; phase 1/2 clinical trials ; skeletal muscle |
Abstract: |
Accès au résumé PubMed / to PubMed abstract |
Lien associé : | http://www.ncbi.nlm.nih.gov/pubmed/20677099 |