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 > MYOBASE > BIOLOGIE > biologie par appareil > appareil locomoteur > muscle > protéine de structure musculaire > protéine sarcomérique > troponine
troponine
Commentaire :
La troponine est une protéine globulaire à forte affinité pour le Ca2+. Elle s'associe avec la tropomyosine pour former des complexes qui sont fixés sur la double hélice d'actine F.
Synonyme(s)troponinVoir aussi |
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Overexpression of the double homeodomain protein DUX4c interferes with myofibrillogenesis and induces clustering of myonuclei
Vanderplanck C, Tassin A, Ansseau E, et al.
Skeletal Muscle, 2018, 8, 1
Cardiac involvement in myotonic dystrophy: The role of troponins and N-terminal pro B-type natriuretic peptide
Valaperta R, De Siena C, Cardani R, et al.
Atherosclerosis, 2017, 267, p 110
The reason for a high Ca2+-sensitivity associated with Arg91Gly substitution in TPM2 gene is the abnormal behavior and high flexibility of tropomyosin during the ATPase cycle
Borovikov YS, Simonyan AO, Karpicheva OE, et al.
Biochemical and biophysical research communications, 2017, 494, 3-4, p 681
Therapeutic approaches for spinal muscular atrophy (SMA)
Scoto M, Finkel RS, Mercuri E, et al.
Gene therapy, 2017, 24, 9, p 514
Sarcomere Dysfunction in Nemaline Myopathy
de Winter JM, Ottenheijm CAC
Journal of Neuromuscular Diseases, 2017, 4, 2, p 99
Progression of Duchenne Cardiomyopathy Presenting with Chest Pain and Troponin Elevation
Hor KN, Johnston P, Kinnett K, et al.
Journal of Neuromuscular Diseases, 2017, 4, 4, p 307
Dramatic elevation in urinary amino terminal titin fragment excretion quantified by immunoassay in Duchenne muscular dystrophy patients and in dystrophin deficient rodents
Robertson AS, Majchrzak MJ, Smith CM, et al.
Neuromuscular disorders : NMD, 2017, 27, 7, p 635
Elevated plasma levels of cardiac troponin-I predict left ventricular systolic dysfunction in patients with myotonic dystrophy type 1: A multicentre cohort follow-up study
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PLoS ONE, 2017, 12, 3
Dissecting the role of the myofilament in diaphragm dysfunction during the development of heart failure in mice
Gillis TE, Klaiman JM, Foster A, et al.
American journal of physiology. Heart and circulatory physiology, 2016, 310, 5, p 572
A cross sectional study of two independent cohorts identifies serum biomarkers for facioscapulohumeral muscular dystrophy (FSHD)
Petek LM, Rickard AM, Budech C, et al.
Neuromuscular disorders : NMD, 2016, 26, 7, p 405
Muscle-Derived Proteins as Serum Biomarkers for Monitoring Disease Progression in Three Forms of Muscular Dystrophy
Burch PM, Pogoryelova O, Goldstein R, et al.
Journal of Neuromuscular Diseases, 2015, 2, 3, p 241
Nemaline myopathy caused byTNNT1 mutations in a Dutch pedigree
van der Pol WL, Leijenaar JF, Spliet WG, et al.
Molecular genetics & genomic medicine, 2014, 2, 2, p 134
Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations
de Winter JM, Buck D, Hidalgo C, et al.
Journal of medical genetics, 2013, 50, 6, p. 383-392
Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases
Russell AJ, Hartman JJ, Hinken AC, et al.
Nature medicine, 2012, 18, 3, p. 452-455
Decoding muscle alternative splicing
Llorian M, Smith CWJ
Current opinion in genetics and development, 2011, 21, 4, p. 380-387
Cardiac involvement in sporadic inclusion-body myositis
Utz W, Schmidt S, Schulz-Menger J, et al.
Circulation, 2010, 121, 5, p. 706-708
Routine and specialized laboratory testing for the diagnosis of neuromuscular diseases in dogs and cats
Diane Shelton G
Veterinary clinical pathology, 2010, 39, 3, p. 278-295
Nebulin alters crossbridge cycling kinetics and increases thin filament activation. A novel mechanism for increasing tension and reducing tension cost
Chandra M, Mamidi R, Ford S, et al.
Journal of biological chemistry (The), 2009, 284, 45, p. 30889-30896
Mécanismes moléculaires de la régulation et de la dérégulation de l'épissage alternatif de Tau et de cTNT dans la Dystrophie Myotonique de Type 1
Ghanem D
Thèse, 2009, 162 p
Thin filament proteins mutations associated with skeletal myopathies : defective regulation of muscle contraction
Ochala J
Journal of molecular medicine, 2008, 86, 11, p. 1197-1204
Circulating autoantibodies to troponin I in Emery-Dreifuss muscular dystrophy
Niebroj-Dobosz I, Marchel M, Madej A, et al.
Acta myologica, 2008, XXVII, p. 1-6
Elévation de troponine I à coronarographie normale chez un patient porteur d'une myopathie de Duchenne
Schoeffler M, Wallet F, Robert MO, et al.
Annales françaises d'anesthésie et de réanimation, 2008, 27, 4, p. 345-347
Selective vacuolar degeneration in dystrophin-deficient canine Purkinje fibers despite preservation of dystrophin-associated proteins with overexpression of Dp71
Urasawa N, Wada MR, Machida N, et al.
Circulation, 2008, 117, 19, p. 2437-2448
