Détail de l'auteur
Auteur Konig S |
Documents disponibles écrits par cet auteur (13)
trié(s) par (Date de parution décroissant(e), Date de parution décroissant(e), Système de projection du document croissant(e)) | Mettre toutes les notices dans le panier | Faire une suggestion | Ajouter un critère de recherche
Article
4th International Congress of Myology, 4ème colloque international de Myologie (9-13 mai 2011; Lille (France)) ; Leroy M ; Darbellay B ; Bernheim L ; Konig S | AFM-TELETHON | 2011Our work focuses on the comprehension of the early steps of myoblast differentiation. The model we use consists of a human myoblast culture derived from satellite cells extracted from muscle biopsies. We previously showed that, to differentiate,[...]Article
4th International Congress of Myology, 4ème colloque international de Myologie (9-13 mai 2011; Lille (France)) ; Konig S ; Brawand P ; Bernheim L | AFM-TELETHON | 2011Our work is based on human primary myoblast cultures derived from single satellite cells. In human, as in other species, it is well established that myoblast differentiation is mainly controlled by two families of transcription factors, the Myog[...]Article
4th International Congress of Myology, 4ème colloque international de Myologie (9-13 mai 2011; Lille (France)) ; Fabrice A ; Konig S ; Bernheim L ; Frieden M | 2011The myogenesis process involves the expression of muscle-specific transcription factors such as myogenin and MEF2, and is essentially regulated by fluctuations of the cytosolic Ca2+ concentration. Previous work demonstrated that hyperpolarizatio[...]Article
Congrès international de myologie 2008 (International Congress of Myology 2008; 26-30 mai 2008; Marseille, France) ; Laumonier T ; Konig S ; Bader C ; Bernheim L ; Hoffmeyer P ; Menetrey J | 2008Cellular therapies for Duchenne muscular dystrophy and other muscle diseases are limited by a massive early cell death following injections. The quantification of cell survival is an essential step to evaluate the efficiency of myoblast transpla[...]Article
Congrès international de myologie 2008 (International Congress of Myology 2008; 26-30 mai 2008; Marseille, France) ; Konig S ; Bader CR ; Bernheim L | 2008Our work is based on human primary myoblast cultures derived from single satellite cells. Human myoblasts are able to proliferate for several weeks in culture, and terminal differentiation into myotubes can be induced by serum withdrawal. In hum[...]Article
Congrès international de myologie 2008 (International Congress of Myology 2008; 26-30 mai 2008; Marseille, France) ; Darbellay B ; Arnaudeau S ; Konig S ; Jousset H ; Bader CR ; Demaurex N ; Bernheim L | 2008Specific intracellular calcium signals are required to induce myoblast differentiation. To generate these calcium signals, myoblasts can rely on two major sources: releases from intracellular calcium stores and influxes from extracellular medium[...]Article
Congrès international de myologie 2005 (International Congress of Myology 2005; 9-13 mai 2005; Nantes, France) ; Hinard V ; Konig S ; Bader C ; Bernheim L | 2005Communication n° 155. During post-natal growth or after muscle injury, skeletal muscle myoblasts differentiate and fuse to form myotubes. We have shown recently that one of the earliest events of the differentiation is the hyperpolarization of h[...]Article
Congrès international de myologie 2005 (International Congress of Myology 2005; 9-13 mai 2005; Nantes, France) ; Arnaudeau S ; Holzer N ; Konig S ; Bader CR ; Bernheim L | 2005Communication n° 137. Myoblast differentiation is a strictly Ca2+-dependent process. We have shown that a main route for Ca2+ entry is through T-type Ca2+ channels. However, because of the importance of cytoplasmic Ca2+ for differentiation, myob[...]Article
Congrès international de myologie 2005 (International Congress of Myology 2005; 9-13 mai 2005; Nantes, France) ; Konig S ; Hinard V ; Beguet A ; Arnaudeau S ; Bader CR ; Bernheim L | 2005Communication n° 144. We have showed previously that human myoblasts must hyperpolarize to approximately -70 mV before they can proceed through the differentiation process. This hyperpolarization occurs through the expression of Kir2.1 K+ channe[...]Article
Congrès international de myologie 2005 (International Congress of Myology 2005; 9-13 mai 2005; Nantes, France) ; Laumonier T ; Yang SH ; Konig S ; Hoffmeyer P ; Menetrey J | 2005Communication n° 157 Introduction : Myoblast transplantation is a widely investigated cell therapy technique for the potential treatment of muscle injury, cardiac failure and inherited myopathies. We have showed recently that pig is an adequate [...]Article
Liu JH ; Konig S ; Michel M ; Arnaudeau S ; Fischer-Lougheed J ; Bader CR ; Bernheim L | 2003Thèse/Mémoire
Konig S, Auteur | 1997Parmi les lésions musculaires observées chez les individus infectés par HTLV-I, environ 64% représentent des atteintes primaires du muscle squelettique (polymyosites ou myopathies non-inflammatoires). La protéine Tax, incapable de se fixer à l'A[...]