Titre : | A Randomized Phase 1 Safety, Pharmacokinetic and Pharmacodynamic Study of the Novel Myostatin Inhibitor Apitegromab (SRK-015): A Potential Treatment for Spinal Muscular Atrophy |
Revue : | Advances in therapy |
Auteurs : | Barrett D ; Bilic S ; Chyung Y ; Cote SM ; Iarrobino R ; Kacena K ; Kalra A ; Long K ; Nomikos G ; Place A ; Still JG ; Vrishabhendra L |
Type de document : | Article |
Editeur : | United States, 08/05/2021 |
Langues: | Anglais |
Mots-clés: | Apitegromab;Human monoclonal antibody;Myostatin;Pharmacodynamics;Pharmacokinetics;Phase 1 study;SRK-015;Safety;Spinal muscular atrophy;Tolerability; |
Pubmed / DOI : | Pubmed : 33963971 / DOI : 10.1007/s12325-021-01757-z |
N° Profil MNM : | 2021052 |
En ligne : | http://www.ncbi.nlm.nih.gov/pubmed/33963971 |