Title: | Unexpected Mutations by CRISPR-Cas9 CTG Repeat Excision in Myotonic Dystrophy and Use of CRISPR Interference as an Alternative Approach |
Journal : | Molecular therapy. Methods & clinical development, 18 |
Authors: | Ikeda M ; Taniguchi-Ikeda M ; Kato T ; Shinkai Y ; Tanaka S ; Hagiwara H ; Sasaki N ; Masaki T ; Matsumura K ; Sonoo M ; Kurahashi H ; Saito F |
Material Type: | Article |
Publication Date: | 2020 |
Size: | p 131 |
Languages: | English |
Keywords: | CRISPR interference;CRISPR-Cas9;DMPK;RNA foci;genome editing;myotonic dystrophy;off-target; |
Pubmed / DOI : | Pubmed : 32637445 / DOI : 10.1016/j.omtm.2020.05.024 |
N° Profil MNM : | 2020071 |
Link for e-copy: | http://www.ncbi.nlm.nih.gov/pubmed/32637445 |