Title: | Discovery of a Novel Class of Survival Motor Neuron 2 Splicing Modifiers for the Treatment of Spinal Muscular Atrophy |
Journal : | Journal of Medicinal Chemistry, 60, 10 |
Authors: | Pinard E, Author ; Green L ; Reutlinger M ; Weetall M ; Naryshkin NA ; Baird J ; Chen KS ; Paushkin SV ; Metzger F ; Ratni H |
Material Type: | Article |
Publication Date: | 2017 |
Size: | p 4444 |
Languages: | English |
Keywords : | alternative splicing ; drug toxicity ; heterocyclic compounds ; SMN protein ; SMN1 gene ; SMN1-related proximal spinal muscular atrophy ; SMN2 gene ; spinal muscular atrophy mouse ; therapeutic prospects |
Pubmed / DOI : | DOI : 10.1021/acs.jmedchem.7b00406 / Pubmed : 28441483 |
Link for e-copy: | http://www.ncbi.nlm.nih.gov/pubmed/28441483 |