Title: | CRISPR/Cas9 Flexes Its Muscles: In Vivo Somatic Gene Editing for Muscular Dystrophy |
Journal : | Molecular therapy : the journal of the American Society of Gene Therapy, 24, 3 |
Authors: | Vandendriessche T, Author ; Chuah MK |
Material Type: | Article |
Publication Date: | 2016 |
Size: | p 414 |
Languages: | English |
Keywords : | adenoassociated vectors ; adverse side effects ; CRISPR/Cas9 ; Duchenne muscular dystrophy ; gene therapy ; therapeutic prospects |
Abstract: |
Comment on:
- CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice. Mol Ther. 2016 Mar;24(3):564-9. - Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy. Science. 2016 Jan 22;351(6271):400-3. - In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy. Science. 2016 Jan 22;351(6271):403-7. - In vivo gene editing in dystrophic mouse muscle and muscle stem cells. Science. 2016 Jan 22;351(6271):407-411. |
Pubmed / DOI : | DOI : 10.1038/mt.2016.29 / Pubmed : 26952918 |
Link for e-copy: | http://www.ncbi.nlm.nih.gov/pubmed/26952918 |
See also : |