Title: | IGF-1 delivery to the CNS attenuates motor neuron cell death but does not improve motor function in type III SMA mice |
Journal : | Neurobiology of disease, 45, 1 |
Authors: | Tsai LK ; Chen YC ; Cheng WC ; Ting CH ; Dodge JC ; Hwu WL ; Cheng SH ; Passini MA |
Material Type: | Article |
Publication Date: | 2012 |
Size: | p. 272-279 |
Languages: | English |
Keywords : | AAV2 vectors ; adenoassociated vectors ; BAX gene ; cell cultures ; cell death ; central nervous system ; gene expression ; gene therapy ; IGF1 ; immunohistochemistry ; motor neuron disease ; mouse model ; phenotypes ; RT-PCR ; spinal cord ; spinal muscular atrophy ; spinal muscular atrophy mouse ; statistics ; Western blot |
Abstract: |
Accès au résumé PubMed / to PubMed abstract |
Lien associé : | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21884794 |
Pubmed / DOI : | DOI : 10.1016/j.nbd.2011.06.021 |