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Auteur Li Z |
Documents disponibles écrits par cet auteur (75)
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Heckmann MB, Auteur ; Bauer R ; Jungmann A ; Winter L ; Rapti K ; Strucksberg KH ; Clemen CS ; Li Z ; Schröder R ; Katus HA ; Muller OJ | 2016Article
Comment in: Inflammatory myopathies: Choosing the right biomarkers to predict ILD in myositis. [Nat Rev Rheumatol. 2016]Article
The mammalian synemin is a very unique intermediate filament (IF) gene encoding three isoforms (H, M and L) achieved by alternative mRNA splicing, exon skipping and an open reading frame shift. Synemin is a desmin-related myopathies (DRM)-associ[...]Article
SRF (Serum Response Factor) is a MADS box transcription factor that regulates the expression of numerous genes involved in contraction, signaling or energy metabolism. Cardiac-specific Cre/loxP mediated inactivation of SRF leads to reduced contr[...]Article
4th International Congress of Myology, 4ème colloque international de Myologie (9-13 mai 2011; Lille (France)) ; Diguet N ; Mallat Y ; Ladouce R ; Clodic G ; Tritsch E ; Blanc J ; Larcher JC ; Delcayre C ; Samuel JL ; Friguet B ; Bolbach G ; Li Z ; Mericskay M | 2011RATIONALE: Alterations in the balance between sarcomeric and extra-sarcomeric cytoskeleton as well as energetic proteins are involved in the remodelling of cardiomyocytes cytoarchitecture in dilated cardiomyopathy (DCM). OBJECTIVE: Inactivation [...]Article
4th International Congress of Myology, 4ème colloque international de Myologie (9-13 mai 2011; Lille (France)) ; Coletti D ; Aulino P ; Mericskay M ; Li Z ; Adamo S | 2011In humans, selenoprotein N (SelN) deficiency, due to mutations in the SEPN1 gene, causes a group of inherited neuromuscular disorders termed SEPN1-RelatedMyopathies. These congenital diseases are characterized by an early onset generalized muscl[...]Article
Izmiryan A ; Peltékian E ; Paulin D ; Li Z ; Xue Z | 2010Accès au résumé PubMed / to PubMed abstractArticle
Izmiryan A ; Paulin D ; Li Z | 2008Desminopathies are subgroups of myofibrillar myopathies caused by mutations in desmin gene. They are characterized by the presence of protein aggregates in muscle cells. Desmin is the main IF protein in mature striated muscle and it is found at [...]Article
Lamotte L ; Escoubet B ; Touvron M ; Rosenthal N ; Lessard J ; Mericskay M ; Li Z ; Daegelen D ; Tuil D | 2008Serum response factor (SRF) is a transcription factor controlling the expression of many extracellular signal-regulated genes as well as genes encoding sarcomeric contractile proteins. Many SRF target genes are involved in familial hypertrophic [...]Article
Congrès international de myologie 2008 (International Congress of Myology 2008; 26-30 mai 2008; Marseille, France) ; Mericskay M ; Blanc J ; Tritsch E ; Moriez R ; Aubert P ; Neunlist M ; Feil R ; Li Z | 2008SRF regulates the expression of muscle genes and immediate early genes and plays a crucial role in the heart and the skeletal muscles. Here, we investigated the consequences of inactivating SRF in adult gastrointestinal smooth muscle cells (SMCs[...]Article
Congrès international de myologie 2008 (International Congress of Myology 2008; 26-30 mai 2008; Marseille, France) ; Galmiche G ; Mericskay M ; Blanc J ; Li Z | 2008Vascular smooth muscle cells (VSMCs) anomalies are directly involved in different forms of myopathies including Duchene myopathy and desminopathies. The alteration of cytoskeletal mechanostransduction and transcriptional pathways play an importa[...]Article
Congrès international de myologie 2008 (International Congress of Myology 2008; 26-30 mai 2008; Marseille, France) ; Li Z ; Kollias H ; Wagner K | 2008Myostatin is a TGF-? family member that negatively regulates muscle growth. Studies in a mouse model of Duchenne and Becker muscular dystrophy (mdx) showed that deletion of myostatin gene or treatment with a postnatal inhibitor of myostatin sign[...]Article
Accès au résumé PubMed / to PubMed abstractArticle
Bhosle RC ; Michele DE ; Campbell KP ; Li Z ; Robson RM | 2006Accès au résumé PubMed / to PubMed abstractArticle
Izmiryan A ; Cheraud Y ; Khanamiryan L ; Leterrier JF ; Federici T ; Peltékian E ; Moura-Neto V ; Paulin D ; Li Z ; Xue ZG | 2006Article
Charvet C ; Houbron C ; Parlakian A ; Giordani J ; Lahoute C ; Bertrand A ; Sotiropoulos A ; Renou L ; Schmitt A ; Melki J ; Li Z ; Daegelen D ; Tuil D | 2006Article
Parlakian A ; Charvet C ; Escoubet B ; Mericskay M ; Molkentin JD ; Gary-Bobo G ; De Windt LJ ; Ludosky MA ; Paulin D ; Daegelen D ; Tuil D ; Li Z | 2005Comment in: Heart failure research continues to reveal the flaws in nature's unintelligent design. Sawyer DB. Circulation. 2005 Nov 8;112(19):2891-3.Article
Congrès international de myologie 2005 (International Congress of Myology 2005; 9-13 mai 2005; Nantes, France) ; Charvet C ; Sotiropoulos A ; Houbron C ; Parlakian A ; Bertrand A ; Lahoute C ; Schmidt A ; Renou L ; Melki J ; Paulin D ; Li Z ; Daegelen D ; Tuil D | 2005Communication n° 497. SRF is a transcriptional factor involved in both cell growth and muscle-specific gene expression. Our previous data obtained in cultured muscle cells showed that SRF is needed for myoblasts differentiation. Classical disrup[...]Article
Congrès international de myologie 2005 (International Congress of Myology 2005; 9-13 mai 2005; Nantes, France) ; Gary-Bobo CL ; Parlakian A ; Mericskay M ; Tuil D ; Daegelen D ; Paulin D ; Li Z | 2005Communication n° 99. Serum response Factor (SRF) is a muscle-enriched transcription factor that plays an important role in the regulation of contractile protein gene expression in mammalian heart. Strong SRF expression was observed in the myocar[...]